Learning the Best way to Host from A different State.

I live I Sunny Florida, but and have a house in Long Island New York, I am trying to find the best way to utilize the space for the visitor. By room or the entire place.
There is an upstairs with 3 bdrm and 2 baths and downs state has 2bedrooms 1 bath, it occupied now but Can be freed up. Any suggestion on how to go about hosting from Florida !and how I should rent the space to Booking, Airbnb, Guest .etc.? Thank you